Riehl melanosis - Riehl Melanose
https://en.wikipedia.org/wiki/Riehl_melanosis
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References
Riehl Melanosis 32491369 NIH
Riehl melanosis er ofte kendt som pigmenteret kontaktdermatitis. Det er en type hudlidelse, der skyldes allergier, typisk udløst af duft og andre stoffer i kosmetiske produkter. Selvom den klassificeres som en form for dermatitis, viser Riehl melanosis kun pigmentforandringer i huden med minimale tegn på irritation. Tilstanden forekommer hyppigere hos personer med mørkere hudtoner. Nyere forskning har undersøgt effektiviteten af mid‑fluence QSNY 1064‑nm laserbehandling til behandling af den dybe pigmentering, der er forbundet med Riehl melanosis. En anden undersøgelse kombinerede flere terapier, herunder low‑fluence 1064‑nm Q‑switched Nd:YAG‑laser, hydroquinoncreme og oral tranexamsyre, hvilket resulterede i en markant forbedring hos de fleste patienter.
Riehl melanosis (RM), commonly called pigmented contact dermatitis, is considered an acquired form of allergic contact dermatitis, typically to fragrance and other ingredients of cosmetic products. Although it is considered as a dermatitis, it presents clinically with hyperpigmentation over the face and shows pigment incontinence with minimal eczematous changes on histology. The condition is more commonly seen in dark-skinned people, causing an important psychosocial impact. A recent study showing the higher effectiveness of mid-fluence QSNY 1064-nm laser in targetting the deep pigmentation of RM has also been conducted. Another study used a combination of therapies to include low-fluence, 1064-nm, Q-switched Nd: YAG laser, hydroquinone cream, and oral tranexamic acid, with the majority of patients experiencing significant improvement.
Research Advances in the Treatment of Riehl’s Melanosis 37168093 NIH
Riehl's melanosis er en hudlidelse, der skyldes kontakt med visse allergener og eksponering for sollys. Den medfører hurtig, progressiv gråbrun pigmentering af huden, hvilket kan påvirke patienterne både mentalt og fysisk i høj grad. Selvom den præcise årsag til Riehl's melanosis stadig er ukendt, viser eksisterende forskning en stærk sammenhæng med allergeneksponering. Til behandling er både traditionel medicin og laserterapi blevet anvendt, ofte i kombination med topisk påføring af blegemidler. Laserterapi, især Q‑switched Nd:YAG‑laser, har vist lovende resultater ved behandling af Riehl's melanosis. Kombination af forskellige behandlingsmetoder har givet positive resultater.
Riehl's melanosis (RM) is a contact photodermatitis, with fast progressive gray-brown skin pigmentation as the main manifestation, which can seriously affect the psychology and physiology of patients. Currently, although the etiological factors of Riehl's melanosis is still be unknown, the existing literature proves clearly the cause of it is related to the contacting with suspected allergens. For decades, there has been no standard method for the treatment of RM, but with both conventional drug therapy and laser therapy having been attempted. Topical application of bleaching agents is mainly used as an auxiliary treatment modality. The laser treatment modality remains a hot spot, among which Q-switched Nd:YAG laser is well received for RM. Positive outcomes have been achieved by the combined treatment modalities attempted in recent years also achieve positive outcomes.