Riehl melanosis - Riehl Melanose
https://en.wikipedia.org/wiki/Riehl_melanosis
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References
Riehl Melanosis 32491369 NIH
Riehl melanosis er ofte kendt som pigmenteret kontaktdermatitis. Det er en type hudlidelse forårsaget af allergier, normalt udløst af duft og andre stoffer, der findes i kosmetiske produkter. På trods af at den er klassificeret som en type dermatitis, viser Riehl melanosis pigmentforandringer i huden med kun mindre tegn på irritation. Det er mere almindeligt hos mennesker med mørkere hudtoner. Nyere forskning har undersøgt effektiviteten af mid-fluence QSNY 1064-nm laserbehandling til behandling af den dybe pigmentering forbundet med Riehl melanosis. En anden undersøgelse kombinerede forskellige terapier, herunder low-fluence 1064-nm Q-switched Nd: YAG laser, hydroquinoncreme og oral tranexamsyre, hvilket resulterede i en betydelig forbedring for de fleste patienter.
Riehl melanosis (RM), commonly called pigmented contact dermatitis, is considered an acquired form of allergic contact dermatitis, typically to fragrance and other ingredients of cosmetic products. Although it is considered as a dermatitis, it presents clinically with hyperpigmentation over the face and shows pigment incontinence with minimal eczematous changes on histology. The condition is more commonly seen in dark-skinned people, causing an important psychosocial impact. A recent study showing the higher effectiveness of mid-fluence QSNY 1064-nm laser in targetting the deep pigmentation of RM has also been conducted. Another study used a combination of therapies to include low-fluence, 1064-nm, Q-switched Nd: YAG laser, hydroquinone cream, and oral tranexamic acid, with the majority of patients experiencing significant improvement.
Research Advances in the Treatment of Riehl’s Melanosis 37168093 NIH
Riehl's melanosis er en type hudlidelse forårsaget af kontakt med visse allergener og eksponering for sollys. Det fører til hurtig, progressiv gråbrun pigmentering af huden, som i høj grad kan påvirke patienterne både mentalt og fysisk. Mens den nøjagtige årsag til Riehl's melanosis stadig er ukendt, indikerer eksisterende forskning en stærk forbindelse med allergeneksponering. Til behandlingen er både traditionel medicin og laserterapi blevet forsøgt, ofte sideløbende med brug af blegemidler påført huden. Laserterapi, især ved brug af Q-switched Nd:YAG laser, har vist lovende resultater til behandling af Riehl's melanosis. Kombination af forskellige behandlingsmetoder har ført til positive resultater.
Riehl's melanosis (RM) is a contact photodermatitis, with fast progressive gray-brown skin pigmentation as the main manifestation, which can seriously affect the psychology and physiology of patients. Currently, although the etiological factors of Riehl's melanosis is still be unknown, the existing literature proves clearly the cause of it is related to the contacting with suspected allergens. For decades, there has been no standard method for the treatment of RM, but with both conventional drug therapy and laser therapy having been attempted. Topical application of bleaching agents is mainly used as an auxiliary treatment modality. The laser treatment modality remains a hot spot, among which Q-switched Nd:YAG laser is well received for RM. Positive outcomes have been achieved by the combined treatment modalities attempted in recent years also achieve positive outcomes.